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2. Hepatitis

Inflammation of liver tissue is hepatitis. Most people know of hepatitis C, but there are four other main types of hepatitis. Hepatitis B is the form that primarily increases bilirubin in the people it affects. Viruses are the most common cause of hepatitis, but certain medications, alcohol use, and autoimmune diseases can also be responsible. The signs and symptoms of hepatitis can vary widely. Many people experience no symptoms at all, while others may experience severe liver failure, sepsis, or cancer.

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