Histoplasmosis is a lung disease caught after breathing in the spores of a fungus. This fungus is most commonly found in the Midwestern USA. Many people breathe in these spores and experience no symptoms so there is no need for medical intervention. The doctor only becomes involved if the condition develops into health-damaging symptoms. Medicine divides the more serious histoplasmosis into three categories: Acute histoplasmosis, Chronic cavitary histoplasmosis, and Disseminated histoplasmosis. The exact symptoms the patient experience, and when they are likely to appear, are some of the key differences between these categories. While histoplasmosis usually takes a mild form, its extreme manifestation can be life-threatening.

1. Running a high fever

The list of illnesses where fever features as a symptom is extremely long with many more common causes than histoplasmosis. The doctor is only likely to investigate this possibility if they know the patient has been in an area where the fungus spores are in the air. They will be particularly concerned for anyone in one of the most at-risk groups. In general, those with weak immune systems are the most likely to be affected seriously. This group includes the very young and the very old and anyone who has undergone an organ transplant.