Gilbert’s disease or Gilbert’s syndrome is a common liver condition also known as constitutional hepatic dysfunction or familial non-hemolytic jaundice. In people with this disease, the liver is unable to process bilirubin, an orange-yellow pigment produced during the breakdown of red blood cells. Normally, the liver breaks bilirubin down so it can be passed out of the body in stools.
People with Gilbert’s disease often have no symptoms. For this reason, it is common to go for many years without a diagnosis. However, if levels of bilirubin in the blood increase, people with Gilbert’s syndrome may notice a slight yellowish coloration to their skin or eyes. Some people experience episodes of mild abdominal discomfort. Certain factors can increase the levels of bilirubin in the bloodstreams of people with Gilbert’s syndrome, including menstruation, common illnesses, and dehydration.